23 Dec 2017 by sammons

Links I really like

UCSC Genome Browser
Ubiquitous and fantastically data rich, UCSC Genome Browser is my go-to.
WashU Epigenome Browswer
Excellent 3D visualization tools as well as host to a number of consortium data hubs
Cancer Cell Line Encyclopedia
Search for your favorite genes and compare expression across multiple cancer cell lines. Very well done.
HOMER
One of the best annotated software suites, this is still my favorite semi-integrated next-gen sequencing analysis software. Bonus for being great at its original function: DNA motif analysis
Bedtools
Indispensable tool for analysis of genomic intervals/peak locations.
Homebrew
Easiest way to install and update command line software tools on Mac.
Homebrew Formulas
Nice list of software that can be installed/managed by homebrew.
Gene Expression Omnibus
NIH-funded repository for genomics data of all types
Sequence Read Archive
NIH-funded repository for next-generation sequencing reads.
deeptools
Very nice suite of tools for some ChIP-seq/RNA-seq applications; many uses!

DEseq2

STAR Aligner
Super fast and accurate aligner: requires high RAM for mammalian genomes, but speed can’t be beat.
Bowtie2
My favorite short read aligner (mainly because I know how to use it).
HOCOMOCO
Nice database of DNA-binding protein motifs
Firebrowse
Integration of (primarily) the Cancer Genome Atlas (TCGA) data
cBioPortal
Integration of TCGA and many other datasets
EMBOSS
Software suite that performs numerous DNA/RNA sequence manipulations
JASPAR
Transcription factor binding motif database
Software Carpentry
Learn how to code (I need to do this)