Determinants of p53 DNA binding, gene regulation, and cell fate decisions

Fischer M and Sammons MA. Cell Death & Differentiation 2024

Context dependent activity of p63-bound gene regulatory elements

McCann AA, et al. bioRxiv 2024

Shared Gene Targets of the ATF4 and p53 Transcriptional Networks

Baniulyte, et al. Molecular and Cellular Biology 2023

A feedback loop between heterochromatin and the nucleopore complex controls germ-cell to oocyte transition during Drosophila oogenesis

Sarkar, et al. Developmental Cell 2023

Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System

Reverdatto, et al. BMC Genomics 2022

p63 and p53 - collaborative partners or dueling rivals?

Woodstock, et al. Front. Cell Dev. Biol 2021

Tumor suppressor p53 - from engaging DNA to target gene regulation

Sammons MA, et al. Nucleic Acids Research 2020

Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

Belrose JL, et al. BMC Genomics 2020

Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line

Bonefant G, et al. Viruses 2020

Smad4-dependent morphogenic signals control the maturation and axonal targeting of basal vomeronasal sensory neurons to the accessory olfactory bulb

Naik, et al. Development 2020

Locally acting transcription factors regulate p53-dependent cis-regulatory element activity

Catizone, et al. Nucleic Acids Research 2020

Targeted identification of protein interactions in eukaryotic mRNA translation

Link, et al. Proteomics 2020

Control of p53-dependent transcription and enhancer activity by the p53 family member p63

Karsli Uzunbas G, et al. Journal of Biological Chemistry 2019

p63 establishes epithelial enhancers at critical craniofacial development genes

Lin-Shiao E, et al. Science Advances, 2019

Comparison of genotoxic vs. non-genotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks

Catizone AN, et al. Cell Cycle 2019

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Fraietta et al. Nature 2018

The transcription factor Tfap2e/AP-2ε plays a pivotal role in maintaining the identity of basal vomeronasal sensory neurons

Lin JM et al. Developmental Biology 2018

Lysine methylation represses p53 activity in teratocarcinoma cancer cells.

Zhu J et al. PNAS 2016

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

Pauken KE et al. Science 2016

A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.

Monteith JA et al. Molecular Oncology 2016

A chromatin-focused siRNA screen for regulators of p53-dependent transcription

Sammons MA et al. G3 2016

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Zhu J et al. Nature 2015

Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest.

Dikovskaya D et al. Cell Reports 2015

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity

Sammons et al. Genome Res 2015